Modified residue | Glycosylation | Lipidation | Crosslink | Disulfide bond

Modified residue (Modified residues excluding lipids, glycans and protein crosslinks.)

Type Description Target Number of experimental sites Number of predicted sites
PhosphorylationPhosphoserineSerine - [Click]20524456114
PhosphorylationPhosphothreonineThreonine - [Click]5498925309
PhosphorylationPhosphotyrosineTyrosine - [Click]3342210352
AcetylationN6-acetyllysineLysine - [Click]2929837932
OtherN6-(pyridoxal phosphate)lysineLysine - [Click]6389148475
AcetylationN-acetylalanineAlanine - [Click]44863222
GlutathionylationS-glutathionyl cysteineCysteine - [Click]411935
HydroxylationHydroxyprolineProline - [Click]34031027
S-nitrosylationS-nitrosocysteineCysteine - [Click]4165459
AcetylationN-acetylmethionineMethionine - [Click]27872274
Hydroxylation4-hydroxyprolineProline - [Click]2740860
AcetylationN-acetylserineSerine - [Click]23801863
Pyrrolidone carboxylic acidPyrrolidone carboxylic acidGlutamine - [Click]2196748
Gamma-carboxyglutamic acid4-carboxyglutamateGlutamate - [Click]1673868
CarboxylationN6-carboxylysineLysine - [Click]163320848
SuccinylationN6-succinyllysineLysine - [Click]15385571
MethylationN6,N6,N6-trimethyllysineLysine - [Click]14433472
MethylationN6-methyllysineLysine - [Click]1380896
MethylationN5-methylglutamineGlutamine - [Click]132714492
AmidationLeucine amideLeucine - [Click]1265234
AmidationAlanine amideAlanine - [Click]1254209
SulfationSulfotyrosineTyrosine - [Click]1211839
PyruvatePyruvic acid (Ser)Serine - [Click]121013068
AmidationPhenylalanine amidePhenylalanine - [Click]1168192
PhosphorylationO-(pantetheine 4'-phosphoryl)serineSerine - [Click]104013193
MethylationSymmetric dimethylarginineArginine - [Click]1019971
MethylationN6,N6-dimethyllysineLysine - [Click]960752
Phosphorylation4-aspartylphosphateAspartate - [Click]9548732
MethylationCysteine methyl esterCysteine - [Click]850806
MethylationAsymmetric dimethylarginineArginine - [Click]847655
AcetylationN-acetylthreonineThreonine - [Click]8234433
Methylation3-methylthioaspartic acidAspartate - [Click]746740
AmidationValine amideValine - [Click]67260
PhosphorylationPhosphohistidineHistidine - [Click]6465140
MethylationN6-methylated lysineLysine - [Click]600380
LipoylationN6-lipoyllysineLysine - [Click]5976357
Pyruvate2-(S-cysteinyl)pyruvic acid O-phosphothioketalCysteine - [Click]5307575
PyrrolylationS-(dipyrrolylmethanemethyl)cysteineCysteine - [Click]4715500
Hydroxylation5-hydroxylysineLysine - [Click]4101828
Methylation5-methylarginineArginine - [Click]400124
MethylationOmega-N-methylated arginineArginine - [Click]369305
CrotonylationN6-crotonyllysineLysine - [Click]342213
OxidationMethionine sulfoneMethionine - [Click]3030
Hydroxylation2,3-didehydroalanine (Ser)Serine - [Click]3022657
AmidationArginine amideArginine - [Click]30085
AmidationGlycine amideGlycine - [Click]29697
MethylationN2,N2-dimethylarginineArginine - [Click]2941
MethylationOmega-N-methylarginineArginine - [Click]291292
AcetylationN-acetylprolineProline - [Click]2882775
AmidationCysteine amideCysteine - [Click]262110
CitrullinationCitrullineArginine - [Click]255319
OtherN6-(retinylidene)lysineLysine - [Click]247379
NitrationNitrated tyrosineTyrosine - [Click]239280
AmidationTryptophan amideTryptophan - [Click]238110
FormylationN-formylmethionineMethionine - [Click]23437
MalonylationN6-malonyllysineLysine - [Click]233167
AmidationAsparagine amideAsparagine - [Click]23352
AmidationIsoleucine amideIsoleucine - [Click]21660
OxidationMethionine sulfoxideMethionine - [Click]211137
AcetylationN-acetylglycineGlycine - [Click]210104
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Glycosylation (Covalently attached glycan group(s).)

Type Description Target Number of experimental sites Number of predicted sites
N-linked GlycosylationN-linked (GlcNAc)Asparagine - [Click]103016100768
O-linked GlycosylationO-linked (GlcNAc)Serine/Threonine/Proline - [Click]5729541
O-linked GlycosylationO-linked (GalNAc)Serine/Threonine - [Click]6871652
O-linked GlycosylationO-linked (Man)Serine/Threonine - [Click]442154
C-linked GlycosylationC-linked (Man)Tryptophan - [Click]44159
N-linked GlycosylationN-linked (GlcNAc) (complex)Asparagine - [Click]25117
N-linked GlycosylationN-linked (Glc)Asparagine - [Click]15534
N-linked GlycosylationN-linked (Glc) (glycation)Asparagine - [Click]1467
N-linked GlycosylationN-linked (GlcNAc) by hostAsparagine - [Click]12014122
N-linked GlycosylationN-linked (GlcNAc) atypicalAsparagine - [Click]1121
O-linked GlycosylationO-linked (GalNAc) partialSerine/Threonine - [Click]8637
N-linked GlycosylationN-linked (GlcNAc) (high mannose)Asparagine - [Click]689
O-linked GlycosylationO-linked (Fuc)Serine/Threonine - [Click]6167
N-linked GlycosylationN-linked (GlcNAc) partialAsparagine - [Click]500
O-linked GlycosylationO-linked (Xyl) (chondroitin sulfate)Serine/Threonine - [Click]4790
O-linked GlycosylationO-linked (HexNAc)Serine/Threonine - [Click]4114
O-linked GlycosylationO-linked (Gal)Serine/Lysine/Proline - [Click]39103
O-linked GlycosylationO-linked (Glc)Serine/Tyrosine - [Click]2880
O-linked GlycosylationO-linked (Hex)Serine/Threonine - [Click]2311
O-linked GlycosylationO-linked (GlcNAc) alternateSerine/Threonine - [Click]20106
N-linked GlycosylationN-linked (GlcNAc) (hybrid)Asparagine - [Click]140
O-linked GlycosylationO-linked (GalNAc) by hostSerine/Threonine - [Click]14133
N-linked GlycosylationN-linked (Glc) (glycation) in PHF-tau in vitroAsparagine - [Click]130
N-linked GlycosylationN-linked (GlcNAc) in isoform SecretedAsparagine - [Click]1312
N-linked GlycosylationN-linked (GlcNAc) (keratan sulfate)Asparagine - [Click]1248
N-linked GlycosylationN-linked (GlcNAc) (polylactosaminoglycan)Asparagine - [Click]110
N-linked GlycosylationN-linked (Man)Asparagine - [Click]116
N-linked GlycosylationN-linked (GlcNAc) (complex) alternateAsparagine - [Click]100
O-linked GlycosylationO-linked (Gal) partialSerine/Lysine/Proline - [Click]100
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Lipidation (Covalently attached lipid group(s).)

Type Description Target Number of experimental sites Number of predicted sites
PalmitoylationS-palmitoyl cysteineCysteine - [Click]34700
PalmitoylationN-palmitoyl cysteineCysteine - [Click]21590
LipoproteinS-diacylglycerol cysteineCysteine - [Click]20140
MyristateN-myristoyl glycineGlycine - [Click]14290
PalmitoylationS-geranylgeranyl cysteineCysteine - [Click]10920
PalmitoylationS-farnesyl cysteineCysteine - [Click]4000
GPI-anchorGPI-anchor amidated serineSerine - [Click]3700
GPI-anchorGPI-anchor amidated asparagineAsparagine - [Click]1680
GPI-anchorGPI-anchor amidated glycineGlycine - [Click]1640
GPI-anchorGPI-anchor amidated alanineAlanine - [Click]890
LipoproteinPhosphatidylethanolamine amidated glycineGlycine - [Click]650
MyristateN6-myristoyl lysineLysine - [Click]580
GPI-anchorGPI-anchor amidated aspartateAspartate - [Click]490
LipoproteinCholesterol glycine esterGlycine - [Click]300
PalmitoylationN-palmitoyl glycineGlycine - [Click]180
GPI-anchorGPI-like-anchor amidated serineSerine - [Click]160
GPI-anchorGPI-anchor amidated cysteineCysteine - [Click]150
GPI-anchorGPI-like-anchor amidated asparagineAsparagine - [Click]150
LipoproteinO-octanoyl serineSerine - [Click]120
LipoproteinS-archaeol cysteineCysteine - [Click]120
PalmitoylationO-palmitoyl serineSerine - [Click]120
PalmitoylationN6-palmitoyl lysineLysine - [Click]110
LipoproteinS-(15-deoxy-Delta12,14-prostaglandin J2-9-yl)cysteineCysteine - [Click]100
LipoproteinS-stearoyl cysteineCysteine - [Click]100
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Cross-link (Residues participating in covalent linkage(s) between proteins.)

Type Description Target Number of experimental sites Number of predicted sites
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Lysine,Lysine.1112072489
CrosslinkIsoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)Lysine,Lysine.1115
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) alternateLysine,Lysine.74266
CrosslinkCyclopeptide (Gly-Asn)Glycine,Asparagine.4741
CrosslinkBeta-methyllanthionine (Thr-Cys)Threonine,Cysteine.2441
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)Lysine,Lysine.211157
CrosslinkLanthionine (Ser-Cys)Serine,Cysteine.1942
CrosslinkCyclopeptide (Gly-Asp)Glycine,Aspartic acid.1211
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) alternateLysine,Lysine.6306
CrosslinkPeptide (Met-Gly) (interchain with G-Cter in ubiquitin)Methionine,Methionine.619
CrosslinkGlycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in ubiquitin)Cysteine,Cysteine.416
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Lysine,Lysine.4154
CrosslinkThiazole-4-carboxylic acid (Gly-Cys)Glycine,Cysteine.40
Crosslink3'-(S-cysteinyl)-tyrosine (Cys-Tyr)Cysteine,Tyrosine.312
CrosslinkCyclopeptide (Ser-Asn)Serine,Asparagine.32
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) in PHF-tauLysine,Lysine.30
CrosslinkOxazole-4-carboxylic acid (Gly-Ser)Glycine,Serine.30
CrosslinkOxazole-4-carboxylic acid (Ser-Ser)Serine,Serine.33
CrosslinkThiazole-4-carboxylic acid (Ser-Cys)Serine,Cysteine.313
Crosslink2-iminomethyl-5-imidazolinone (Gln-Gly)Glutamine,Glycine.23
Crosslink2-iminomethyl-5-imidazolinone (Met-Gly)Methionine,Glycine.20
Crosslink5-methyloxazole-4-carboxylic acid (Cys-Thr)Cysteine,Threonine.22
CrosslinkCyclopeptide (Lys-Asp)Lysine,Aspartic acid.20
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15)Lysine,Lysine.2221
CrosslinkGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2 and SUMO3)Lysine,Lysine.217
CrosslinkIsoglutamyl cysteine thioester (Cys-Gln)Cysteine,Glutamine.240
CrosslinkIsoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-312)Glutamine,Glutamine.20
CrosslinkIsoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-89)Glutamine,Glutamine.20
CrosslinkThiazole-4-carboxylic acid (Thr-Cys)Threonine,Cysteine.28
CrosslinkTryptophan tryptophylquinone (Trp-Trp)Tryptophan,Tryptophan.24
Crosslink1'-histidyl-3'-tyrosine (His-Tyr)Histidine,Tyrosine.1218
CrosslinkGlycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)Glycine,Glycine.1995
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Disulfide bond (Cysteine residues participating in disulfide bonds.)

Type Description Target Number of experimental sites Number of predicted sites
DISULFIDE BONDDISULFIDE BONDCystine,Cystine1669145317
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Modified residue | Glycosylation | Lipidation | Crosslink | Disulfide bond