General Information
PTM Description
4-carboxyglutamate
Modified Amino Acid
E
Position of Modification on Amino Acid
amino-acid side chain
Position in the Polypeptide
any position
Correction Formula
C1;O2
Monoisotopic Mass Difference
43.9898
Average Mass Difference
44.01
Localization
extracellular and lumenal localisation [Detail]
RESID IDAA0032
Formula Structure
Formula 3D Structure
Substrate Site Specificity
Number of Experimentally Validated Sites448
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.080.120.0200.10.0100.110.090.010.030.030
R0.080.120.130.030.020.1600.120.10.120.030.020.01
N0.050.080.10.020.090.0200.030.020.020.050.050.06
D0.030.010.020.010.030.0200.020.010.030.040.010.05
C00.020.10.170.090.0200.090.110.180.010.010.1
G0.010.080.030.10000.01000.080.080
E0.370.170.240.280.090.2710.260.10.290.250.180.38
Q0.020.020.030.020.010.0100.020.010.030.050.020.02
H0.0100.0200.010000.020.010.010.010.02
I0.010.030.0200.030.0200.040.0400.050.040.01
L0.130.030.020.110.120.1900.060.080.010.020.050.09
K0.030.050.060.050.040.0300.040.060.090.070.030.03
M0.010000.020.0200.010.0200.0200
F0.030.070.060.060.10.1100.060.110.030.050.170.07
P0.0200.0200.010.0200.010.020.030.030.020.02
S0.060.060.090.10.10.0200.040.030.070.110.060.03
T0.010.030.030.020.050.0300.030.090.020.010.090.02
W000000.01000.040.01000.05
Y0.020.030.010.010.030.04000.010.010.030.070
V0.030.050.020.030.060.0200.070.050.030.070.050.02
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo