PTM General Information
PTM Description Lysine methyl ester
Modified Amino Acid K
Position of Modification on Amino Acid protein backbone
Position in the Polypeptide C-terminal carboxyl group
Correction Formula C1;H2
Monoisotopic Mass Difference 14.0156
Average Mass Difference 14.03
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0318
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10
A1001100
R0000000
N0000000
D0000000
C0000000
G0000000
E0000000
Q0100000
H0000000
I0000000
L0000000
K0010010
M0000000
F0000000
P0000000
S0000000
T0000000
W0000000
Y0000000
V0000000
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description N6,N6,N6-trimethyllysine
Modified Amino Acid K
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C3;H6
Monoisotopic Mass Difference 42.047
Average Mass Difference 42.08
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0074
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.140.10.040.140.250.0200.070.110.010.090.010.22
R0.020.010.020.0600.2700.0300.070.120.110.06
N000.140.040.16000.010.010.0100.030.02
D0.120.03000.030.0400.020.050.110.10.020.02
C00.0100000000000
G0.040.040.020.10.320.02000.050.110.140.180.11
E0.090.020.010.040.010.1200.010.020.020.150.120.02
Q00.010.110.0400.0200.030.030.0800.030.04
H000.010.010.020000.010.06000
I0.030.070.030.010.020.0200.020.030.150.0100.05
L0.020.030.150.210.030.1100.10.060.050.030.040.04
K0.060.140.150.010.020.0100.30.020.030.080.160.02
M0.2100.0200000.010.010.02000
F0.0100.100.010.0800.020.030.010.010.040.02
P0.070.020.010.110.040.15000.180.160.170.020.01
S0.010.040.060.020.05000.2300.040.050.040.01
T0.10.210.060.1400.0100.050.230.020.020.110.16
W000000.0200.0100.01000
Y00.1500.020.020.0100.010.14000.070.08
V0.070.10.030.050.010.0800.050.020.030.0200.12
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description N6,N6-dimethyllysine
Modified Amino Acid K
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C2;H4
Monoisotopic Mass Difference 28.0313
Average Mass Difference 28.06
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0075
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.140.10.070.120.280.0300.120.170.040.10.060.15
R0.060.020.010.030.010.2800.020.030.080.170.030.12
N0.030.020.030.040.030.0200.0100.010.010.040.08
D0.080.060.040.040.060.0300.030.080.020.060.040.01
C0000000000.01000
G0.050.020.120.140.130.0800.040.030.20.150.040.14
E0.090.080.050.040.04000.040.050.060.10.020.02
Q0.020.020.120.050.030.0300.020.020.020.020.040.06
H00.02000.040.0100.010.010.100.010.01
I0.030.10.020.080.030.02000.040.060.070.030.05
L0.050.040.050.040.080.0500.080.070.090.010.050.09
K0.040.170.160.070.050.1300.160.050.020.070.140.03
M0.0200.0100.01000.010.060.020.020.070.02
F0.010.020.010.020.010.08000.020.0200.090.04
P0.120.040.040.040.010.0400.050.130.120.030.010.04
S0.060.080.090.080.140.0600.280.010.080.060.070.04
T0.120.170.120.150.020.0100.070.140.010.030.120.03
W0.01000000000.01000
Y0.010.020.010.020000.020.020.010.050.080
V0.050.020.040.030.040.100.050.050.030.040.050.06
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description N6-methylated lysine
Modified Amino Acid K
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C3;H6
Monoisotopic Mass Difference 42.047
Average Mass Difference 42.08
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID none
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.230.120.090.210.330.0400.140.210.090.180.110.19
R0.020.050.070.040.040.400.020.040.050.050.040.04
N0.020.050.0200.09000.050.0400.020.020.02
D00.020.050.050.020.0200.020.040.050.050.050.11
C000.04000.040000000.02
G0.110.120.050.110.190.0700.050.070.190.1600.12
E0.050.110.0400.020.0700.050.1100.050.090
Q000.1400000.040.040.0500.040
H0.020.020.0400.040.020000.040.0200
I0.02000.020.02000.0200.070.070.050.02
L0.0400.050.1600.0900.050.040.050.0200.04
K0.050.190.190.050.090.1200.140.050.120.050.180.19
M0.040000000.05000.020.020
F000.0500000.020.040.020.040.090.04
P0.110.070.040.070.040000.070.110.090.070.04
S0.050.120.050.070.040.0400.210.050.090.050.040.04
T0.140.120.040.190.050.0500.040.180.020.020.140.04
W0.0200000000.020000
Y0.0400.0400000000.050.040
V0.0700.020.040.050.0500.110.040.050.070.050.12
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description N6-methyllysine
Modified Amino Acid K
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C1;H2
Monoisotopic Mass Difference 14.0156
Average Mass Difference 14.03
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0076
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.140.120.090.140.220.0900.090.160.080.10.080.16
R0.080.030.050.080.030.2400.030.030.10.120.050.09
N0.030.030.020.030.030.0100.020.020.020.010.040.02
D0.010.030.040.030.060.0200.050.060.040.060.050.04
C0.010.010.01000.010000.01000
G0.10.060.080.120.120.0400.050.040.150.090.050.17
E0.080.050.040.080.040.0500.030.050.050.070.10.03
Q0.020.020.10.040.020.0300.080.010.050.020.030.05
H0.010.010.010.010.05000.030.030.090.010.020.01
I0.020.060.020.040.030.0100.010.050.030.040.020.06
L0.070.040.030.110.080.0800.050.120.070.060.050.05
K0.050.150.180.070.060.0600.130.060.070.090.150.08
M0.040.010.0100.020.0100.010.020000
F0.010.010.010.0100.0800.010.020.040.030.060.01
P0.080.080.040.030.060.0600.040.10.080.040.010.05
S0.060.060.070.040.040.0500.190.040.030.10.070.04
T0.10.140.090.090.040.0600.060.130.020.080.090.06
W000000.01000.0100.010.010
Y0.040.020.050.030.020.0100.020.010.010.030.070.02
V0.040.070.070.040.070.0700.080.060.080.040.040.05
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo




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