PTM General Information
PTM Description 5-methylarginine
Modified Amino Acid R
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C1;H2
Monoisotopic Mass Difference 14.0156
Average Mass Difference 14.03
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0272
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.030.090.050.060.10.0500.070.070.080.060.060.05
R0.150.10.190.090.180.0600.040.220.070.180.090.14
N0.020.030.030.030.010.0300.010.010.030.020.030.04
D0.050.030.030.020.030.0700.020.020.030.040.040.05
C0000.010.010000.010000
G0.250.260.180.290.230.3200.560.310.230.220.290.21
E0.040.040.040.020.050.0200.020.020.040.040.030.04
Q0.050.050.030.050.020.0400.020.040.020.040.050.05
H0.010.010.0100.010.0100.010.020.020.010.030.01
I0.030.020.020.010.020.0300.010.020.010.010.020.01
L0.050.030.050.030.030.0500.050.060.070.040.040.05
K0.040.020.040.050.030.0200.030.030.020.040.040.06
M0.030.030.020.030.030.0100.020.010.040.020.020.03
F0.020.050.030.050.010.0300.020.030.090.030.040.06
P0.080.050.10.080.080.100.060.050.080.080.070.06
S0.060.10.080.090.080.100.020.030.080.060.070.07
T0.040.020.040.020.010.0200.010.030.020.030.050.02
W000000000.010000.02
Y0.030.030.060.030.030.0200.010.010.050.030.010.02
V0.030.040.020.040.040.0200.020.030.030.050.030.02
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description Asymmetric dimethylarginine
Modified Amino Acid R
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C2;H4
Monoisotopic Mass Difference 28.0313
Average Mass Difference 28.05
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0068
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A00.020.020.010.30.0200.0300.020.050.020.02
R0.20.040.130.40.110.0300.080.150.10.130.050.08
N0.010.460.010.020.090.0100.010.010.0100.040.02
D0.020.020.010.010.020.0700.0100.030.020.020.03
C000.2500000000.260.180
G0.370.260.180.160.320.1800.40.30.340.20.210.16
E0.010.010.0200.0100000000.01
Q00.010000.1500.010.060.010.010.010.01
H000000.010000.010.0100
I00.0100.0100.02000.090.070.0100
L0.02000.010.010.010000.0800.010.02
K0.110.010.010.210.010.0100.420.220.010.20.030.3
M0.030.030.040.010.030.02000.020.010.010.010.02
F0.020.010.210.050.010.0200.010.010.070.010.020.19
P0.060.060.050.040.020.3900.010.020.070.030.030.05
S0.050.040.040.040.040.0500.010.010.030.030.050.04
T0.070.0100.010.01000.010.070.010.010.060.01
W00000000000.010.250.01
Y0.030.010.020.0100.0100.010.020.030.030.010.02
V0.0100.010.010.01000.010.010.1300.010.01
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description Dimethylated arginine
Modified Amino Acid R
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C2;H4
Monoisotopic Mass Difference 28.0313
Average Mass Difference 28.05
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID none
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A00.060.10.10.10.0300.030.160.10.060.030.06
R0.10.10.060.130.10.0600.060.060.060.060.10.03
N0.030.10.1000.03000.030.030.060.060.03
D000.030.030.030.030000.030.0300.03
C0000000000.030.0300.03
G0.190.350.060.230.190.3200.740.480.230.350.350.32
E0.060.060.030.060.060.0300.0300.030.10.030.06
Q0.060.030.0300.030.030000.030.030.030.06
H00.030.0300.03000.030.030.0300.030
I0.0300000000.030.030.0300
L0.0300.060.030.030.03000.10.03000.03
K00.030.030.0300000.03000.030.03
M0.0300.030.060.03000.030000.030
F0.030.030.10.1000000.060.10.030.1
P0.060.030.100.060.100.0300.060.10.10
S0.10.030.130.160.230.2300.030.030.100.030.1
T0.130.030.030.0600.03000000.060.03
W0000000000000.03
Y0.060.10.0300.060.060000.1300.060
V0.0600.0300.030000.0300.0300.03
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description N2,N2-dimethylarginine
Modified Amino Acid R
Position of Modification on Amino Acid protein backbone
Position in the Polypeptide N-terminal amino group
Correction Formula C2;H4
Monoisotopic Mass Difference 28.0313
Average Mass Difference 28.06
Localization extracellular and lumenal localisation [Detail]
RESID ID AA0569
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.0+1+2+3+4+5+6
A00.060.050.070.050.070.05
R00.010.250.080.190.080.17
N00.010.030.030.030.050.04
D00.030.010.030.020.040.03
C000.01000.010
G00.630.330.260.260.30.22
E00.020.010.030.020.030.04
Q00.010.030.030.040.040.02
H000.010.010.010.010.01
I00.020.010.010.010.020.01
L00.030.030.050.040.020.04
K00.030.030.020.030.040.05
M000.020.030.020.020.03
F00.020.010.10.030.050.05
P00.040.030.110.060.050.07
S00.020.050.060.040.090.07
T00.020.040.030.030.030.04
W00.01000.0100.01
Y00.020.040.020.050.020.03
V00.030.020.030.030.030.03
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description Omega-N-methylarginine
Modified Amino Acid R
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C1;H2
Monoisotopic Mass Difference 14.0156
Average Mass Difference 14.03
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0069
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.040.060.060.080.020.04000.080.060.060.060.08
R0.040.020.130.120.150.04000.130.060.150.080.19
N0.020.020.02000000.020.020.040.060.02
D0.020.020.040.020.020.0400.02000.040.020.04
C0000.02000000.02000.02
G0.290.190.080.350.210.4400.790.270.150.210.290.15
E0.080.060.080.020.04000.060.020.040.0600.02
Q0.060.060.130.020.020.02000.020.0800.020.06
H00.02000000.020.040000
I0.0200.0400.020000.020.020.020.040.02
L0.040.040.040.020.060.06000.170.040.1700.08
K00.040.020.10.150.0200.020.0600.040.120.02
M0.020.080.020.020.080.04000.040.100.020.04
F0.040.020.040.0400.0600.0200.10.0800.08
P0.190.020.150.10.040.1200.060.040.080.040.060.04
S0.040.190.060.120.10.0800.020.020.170.060.130.08
T0.080.120.0600.020.06000.0600.020.080.04
W0000000000000.02
Y00.02000.0200000.04000
V0.040.040.0400.060000.020.040.020.040.02
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description Omega-N-methylated arginine
Modified Amino Acid R
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C2;H4
Monoisotopic Mass Difference 28.0313
Average Mass Difference 28.06
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0067
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.040.130.070.050.150.0400.050.050.090.050.050.04
R0.160.110.130.050.070.0700.020.20.040.070.040.11
N0.020.040.0500.020.0400.020.040.040.020.070.02
D0.040.040.020.020.040.0200.0400.050.110.020.05
C000.02000000.02000.020
G0.150.180.150.180.180.2500.470.290.240.180.180.16
E0.050.020.020.050.04000.040.050.050.0500.04
Q0.090.040.040.150.020.1100.020.0200.090.090.07
H00.070.0900.020.02000.0400.020.020.02
I0.020.020.020.040.050000.0200.020.040.02
L0.0500.0400.020.0900.070.070.090.040.040.05
K0.050.040.050.020.040.0400.020.020.020.050.020.07
M0.020.040.040.0400.0400.0200.070.020.020.04
F0.020.040.040.0700.0400.090.040.070.020.070.11
P0.110.050.090.070.150.0900.040.020.090.070.050.02
S0.050.090.090.130.090.1100.020.040.130.090.160.09
T0.020.020.020.050000.040.0500.020.040.02
W000000000.020000.02
Y0.020.020.040.040.050.0400.02000.020.020
V0.090.0700.040.070.0200.040.020.020.050.050.05
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo



PTM Description Symmetric dimethylarginine
Modified Amino Acid R
Position of Modification on Amino Acid amino-acid side chain
Position in the Polypeptide any position
Correction Formula C2;H4
Monoisotopic Mass Difference 28.0313
Average Mass Difference 28.06
Localization cytoplasm, nucleus, mitochondrial matrix, etc. [Detail]
RESID ID AA0067
Formula Structure
Formula 3D Structure
Substrate Site Specificity
The Matrix of Positional Amino Acid Frequency Surrounding Modified Site
Pos.-6-5-4-3-2-10+1+2+3+4+5+6
A0.020.030.020.010.280.0400.0300.030.060.030.02
R0.20.050.130.350.10.0300.070.140.090.110.040.11
N0.010.40.010.020.080.0100.010.020.0100.040.02
D0.020.020.010.010.020.0600.0100.030.020.020.03
C000.2200000000.220.160
G0.340.240.170.20.280.2300.430.260.310.20.20.14
E0.010.010.020.010.01000.010.010.010.0100.02
Q00.010.040.0200.1300.010.060.010.010.010.02
H000000.0100.0100.010.0100.01
I0.010.0200.010.010.02000.080.060.0100
L0.020.0100.010.020.01000.050.070.050.020.02
K0.090.010.020.180.050.0100.390.20.010.180.030.28
M0.020.030.030.020.030.02000.030.010.010.010.02
F0.020.010.190.050.020.0200.010.010.060.010.020.17
P0.090.050.060.030.020.3400.010.020.060.020.050.05
S0.050.080.040.060.030.0500.010.030.060.030.090.04
T0.060.0300.010.030.0100.010.070.030.020.060.02
W00000000.01000.010.220.01
Y0.030.010.020.0100.0100.010.020.030.020.010.02
V0.0100.010.020.02000.010.010.1100.010.01
Sequence Logo

Average Solvent Accessibility Surrounding Modified Site
Secondary Structure Logo




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