Subcellular Localization : Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules (By similarity).
Protein Function : Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).
Related Literatures of Post-Translational Modification
"The amino acid sequence of the delta subunit (calmodulin) of rabbitskeletal muscle phosphorylase kinase."; Grand R.J.A., Shenolikar S., Cohen P.; Eur. J. Biochem. 113:359-367(1981). Cited for: PROTEIN SEQUENCE OF 2-149, AND METHYLATION AT LYS-116.