Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures
Basic Information
Protein Name :  Cholinephosphotransferase 1  

UniProtKB / Swiss-Prot ID :  CHPT1_HUMAN

Gene Name (Synonyms) : 
CHPT1, CPT1 MSTP022  

Species :  Homo sapiens (Human). 

Subcellular Localization :  Golgi apparatus membrane; Multi-pass membrane protein. 

Protein Function :  Catalyzes phosphatidylcholine biosynthesis from CDP- choline. It thereby plays a central role in the formation and maintenance of vesicular membranes. 

Transmembrane Topology (topPTM) : CHPT1_HUMAN 

Protein Sequence MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLG...
Predicted Secondary Structure CCCCCCCCCCCHHHHCCCCCCCHHHHCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH...
Protein Variant
LocationDescription
162F -> S (in dbSNP:rs3205421). VAR_032612
323Y -> S (in MCF-12A cell line). VAR_032613
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Overview of Protein Modification Sites with Functional and Structural Information
Accessible Surface Area (ASA)
Pred. Secondary
Real Secondary
Disorder Prediction
Protein Domain
&
Experimental PTM Sites
Predicted PTM Sites
Protein Variant
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Experimental Post-Translational Modification Sites Download
Locations
Modification
Substrate Sites
&
Secondary Structure
Accessible Surface Area (%)
Resource
Reference
Structural Characterization
Orthologous
Protein Cluster
2N-acetylalanine.---MAAGAG
---CCCCCC
18.01UniProtKB
Link-
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Protein-Protein Interactions
      Interacting Protein      
Interaction type
Source ID
      Resource      
      Pubmed ID      
Domain-Domain Interactions
LIS1_HUMANENSP00000229266STRING
DGKB_HUMANENSP00000229266STRING
PA1B3_HUMANENSP00000229266STRING
PLD2_HUMANENSP00000229266STRING
LCAT_HUMANENSP00000229266STRING
DGKD_HUMANENSP00000229266STRING
DGKG_HUMANENSP00000229266STRING
DGKQ_HUMANENSP00000229266STRING
PAFA_HUMANENSP00000229266STRING
DGKE_HUMANENSP00000229266STRING
DGKI_HUMANENSP00000229266STRING
PCY1A_HUMANENSP00000229266STRING
PCY1A_HUMANENSP00000229266STRING
LPP3_HUMANENSP00000229266STRING
PA1B2_HUMANENSP00000229266STRING
DGKZ_HUMANENSP00000229266STRING
PTSS1_HUMANENSP00000229266STRING
DGKH_HUMANENSP00000229266STRING
DGKH_HUMANENSP00000229266STRING
PLD1_HUMANENSP00000229266STRING
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Disease Reference
Kegg disease
There are no disease associations of PTM sites.
Drug Reference
There are no disease associations of PTM sites.
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Related Literatures of Post-Translational Modification
Acetylation
ReferencePubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, AND MASS SPECTROMETRY.
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Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures