| Protein Name :
Peroxisomal 2,4-dienoyl-CoA reductase
UniProtKB / Swiss-Prot ID : DECR2_HUMAN
Gene Name (Synonyms) :
Species : Homo sapiens (Human).
Subcellular Localization : Peroxisome (By similarity).
Protein Function : Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.