Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures
Basic Information
Protein Name :  FYVE and coiled-coil domain-containing protein 1  

UniProtKB / Swiss-Prot ID :  FYCO1_MOUSE

Gene Name (Synonyms) : 
Fyco1  

Species :  Mus musculus (Mouse). 

Subcellular Localization :  Cytoplasmic vesicle, autophagosome (By similarity). Endosome (By similarity). Lysosome (By similarity). Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on t 

Protein Function :  May mediate microtubule plus end-directed vesicle transport (By similarity). 

Protein Sequence MASSSTETQLQRIIRDLQDAATELSHEFKEGGEPITDDSTSLHKFSYKLEYLLQFDQKEKASLLGSKKDY...
Predicted Secondary Structure CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCH...
Protein Variant -
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Overview of Protein Modification Sites with Functional and Structural Information
Accessible Surface Area (ASA)
Pred. Secondary
Real Secondary
Disorder Prediction
Protein Domain
&
Experimental PTM Sites
Predicted PTM Sites
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Experimental Post-Translational Modification Sites Download
Locations
Modification
Substrate Sites
&
Secondary Structure
Accessible Surface Area (%)
Resource
Reference
Structural Characterization
Orthologous
Protein Cluster
190PhosphotyrosineSTSAYMWKP
CCCCCCCCC
11.86Phosphositeplus
Link-
196PhosphoserineWKPPSRSSS
CCCCCCCHH
54.01Phosphositeplus
Link-
372PhosphothreonineKGEKTPPDT
HCCCCCCCC
35.43PhosphoELM
Link-
372PhosphothreonineKGEKTPPDT
HCCCCCCCC
35.43Phosphositeplus
Link-
372Phosphothreonine.KGEKTPPDT
HCCCCCCCC
35.43UniProtKB
Link-
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Protein-Protein Interactions
      Interacting Protein      
Interaction type
Source ID
      Resource      
      Pubmed ID      
Domain-Domain Interactions
There are no Protein-Protein Interactions.
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Disease Reference
Drug Reference
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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-372, AND MASSSPECTROMETRY.
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Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures