Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures
Basic Information
Protein Name :  Vitamin K-dependent protein Z  

UniProtKB / Swiss-Prot ID :  PROZ_HUMAN

Gene Name (Synonyms) : 
PROZ  

Species :  Homo sapiens (Human). 

Subcellular Localization :  Secreted. 

Protein Function :  Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. 

Protein Sequence MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEARE...
Predicted Secondary Structure CCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEE...
Protein Variant
LocationDescription
70E -> K (in dbSNP:rs3024778). VAR_013124
295R -> H (in dbSNP:rs3024772). VAR_013125
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Overview of Protein Modification Sites with Functional and Structural Information
Accessible Surface Area (ASA)
Pred. Secondary
Real Secondary
Disorder Prediction
Protein Domain
&
Experimental PTM Sites
Predicted PTM Sites
Protein Variant
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Experimental Post-Translational Modification Sites Download
Locations
Modification
Substrate Sites
&
Secondary Structure
Accessible Surface Area (%)
Resource
Reference
Structural Characterization
Orthologous
Protein Cluster
474-carboxyglutamate.SYLLEELFE
CEEEEEEEE
50.49UniProtKB
Link-
484-carboxyglutamate.YLLEELFEG
EEEEEEEEC
59.74UniProtKB
Link-
514-carboxyglutamate.EELFEGNLE
EEEEECCCC
60.85UniProtKB
Link-
554-carboxyglutamate.EGNLEKECY
ECCCCCCCC
51.30UniProtKB
Link-
574-carboxyglutamate.NLEKECYEE
CCCCCCCCC
32.72UniProtKB
Link-
604-carboxyglutamate.KECYEEICV
CCCCCCCCC
53.17UniProtKB
Link-
614-carboxyglutamate.ECYEEICVY
CCCCCCCCC
18.40UniProtKB
Link-
664-carboxyglutamate.ICVYEEARE
CCCCCEEEE
25.45UniProtKB
Link-
674-carboxyglutamate.CVYEEAREV
CCCCEEEEC
35.03UniProtKB
Link-
704-carboxyglutamate.EEAREVFEN
CEEEECCCC
59.62UniProtKB
Link-
734-carboxyglutamate.REVFENEVV
EECCCCCCE
58.62UniProtKB
Link-
754-carboxyglutamate.VFENEVVTD
CCCCCCEEE
31.03UniProtKB
Link-
804-carboxyglutamate.VVTDEFWRR
CEEECCCCC
37.43UniProtKB
Link-
93O-linked (GalNAc...)SPCISQPCL
CCCCCCCCC
34.48HPRD
Link-
93O-linked (Glc...).SPCISQPCL
CCCCCCCCC
34.48UniProtKB
Link-
93O-linked (Xyl...) (glycosaminoglycan)SPCISQPCL
CCCCCCCCC
34.48OGlycBase
Link-
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Protein-Protein Interactions
      Interacting Protein      
Interaction type
Source ID
      Resource      
      Pubmed ID      
Domain-Domain Interactions
VKGC_HUMANENSP00000344458STRING
ZPI_HUMANENSP00000344458STRING
B3AT_HUMANENSP00000344458STRING
FURIN_HUMANENSP00000344458STRING
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Disease Reference
Kegg disease
There are no disease associations of PTM sites.
Drug Reference
There are no disease associations of PTM sites.
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Related Literatures of Post-Translational Modification
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Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures