Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures
Basic Information
Protein Name :  Troponin I, cardiac muscle  

UniProtKB / Swiss-Prot ID :  TNNI3_RABIT

Gene Name (Synonyms) : 
TNNI3  

Species :  Oryctolagus cuniculus (Rabbit). 

Subcellular Localization :   

Protein Function :  Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. 

Protein Sequence ADESRDAAGEARPAPAPVRRRSSANYRAYATEPHAKSKKKISASRKLQLKTLMLQIAKQELEREAEERRG...
Predicted Secondary Structure CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH...
Protein Variant -
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Overview of Protein Modification Sites with Functional and Structural Information
Accessible Surface Area (ASA)
Pred. Secondary
Real Secondary
Disorder Prediction
Protein Domain
&
Experimental PTM Sites
Predicted PTM Sites
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Experimental Post-Translational Modification Sites Download
Locations
Modification
Substrate Sites
&
Secondary Structure
Accessible Surface Area (%)
Resource
Reference
Structural Characterization
Orthologous
Protein Cluster
1N-acetylalanine.----ADESR
----CCCCC
40.35UniProtKB
Link-
22PhosphoserineVRRRSSANY
HHHHHHHHH
31.80Phosphositeplus
Link-
22Phosphoserine (PKA_group)VRRRSSANY
HHHHHHHHH
31.80PhosphoELM
Link-
77PhosphoserineGRALSTRCQ
HHHHHHCCC
16.90Phosphositeplus
Link-
77Phosphoserine (PHK_group)GRALSTRCQ
HHHHHHCCC
16.90PhosphoELM
Link-
143PhosphothreonineFKRPTLRLR
EECCCCCCC
28.66Phosphositeplus
Link-
151PhosphoserineRVRISADAM
CCEECHHHH
14.99Phosphositeplus
Link-
151Phosphoserine (PKA_group)RVRISADAM
CCEECHHHH
14.99PhosphoELM
Link-
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Protein-Protein Interactions
      Interacting Protein      
Interaction type
Source ID
      Resource      
      Pubmed ID      
Domain-Domain Interactions
There are no Protein-Protein Interactions.
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Disease Reference
Drug Reference
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Related Literatures of Post-Translational Modification
Acetylation
ReferencePubMed
"A common motif of two adjacent phosphoserines in bovine, rabbit andhuman cardiac troponin I.";
Mittmann K., Jaquet K., Heilmeyer L.M.G. Jr.;
FEBS Lett. 273:41-45(1990).
Cited for: PROTEIN SEQUENCE OF 6-36, ACETYLATION AT ALA-1, AND PHOSPHORYLATION ATSER-22 AND SER-23.
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Basic Information | Overview of PTM Sites | Experimental PTM Sites | Protein-Protein Interactions | Drug and Disease Associations | Related Literatures