Subcellular Localization : Cytoplasm. Nucleus. Note=Translocates to the nucleus in responce to gamma-irradiation (By similarity).
Protein Function : Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited (By similarity).